Research Assistant - Microbiology and Immunology (Dudek Lab)
The laboratory of Dr. Amanda Dudek in the Department of Microbiology and Immunology at the University of Iowa is seeking an experienced and highly motivated Research Assistant to join her team. The Dudek lab uses gene editing to probe the host cell-virus interface to understand early stages of viral replication of HIV-1 and Adeno-associated virus vectors. We aim to use basic mechanistic biology to question 1) how do AAV vectors target and enter various cell types and 2) how does the cell react to AAV vector transduction? We use gene editing of immortalized cell lines as well as hematopoietic stem and progenitor cells (HSPCs) to investigate capsid specific differences in entry pathway usage, as well as mechanisms of cellular toxicity occurring in sensitive primary cell types such as HSPCs. It is our goal to improve the efficacy of viral vectors first by identifying areas of inefficiency and toxicity that are currently limiting broader implementation of AAV-based therapies in the field.
- Research reagent ordering and lab organization.
- Be involved in the preparation and dissemination of scientific manuscripts and presentations.
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Regular salaried position located in Iowa City, Iowa
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Fringe benefit package including paid vacation; sick leave; health, dental, life and disability insurance options; and generous employer contributions into retirement plans
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- Bachelor’s degree in a bio or biomedical sciences with an interest in gene therapy and gene editing
- Excellent written and verbal communication skills
- Background in molecular techniques (e.g., PCR, protein purification, western blot)
- Some background using primary or immortalized animal or human tissues or cell lines
Application Process: Please attach an updated resume/CV as part of the application process. Job openings are posted for a minimum of 14 calendar days. This job may be removed from posting and filled any time after the minimum posting period has ended. Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check. This position is not eligible for University sponsorship for employment authorization
to learn more about this position and apply please contact anne-beyerink@uiowa.edu
Equal opportunity/affirmative action employer
The University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, religion, national origin, age, sex, pregnancy (including childbirth and related conditions), disability, genetic information, status as a U.S. veteran, service in the U.S. military, sexual orientation, gender identity, or associational preferences.
Persons with disabilities who need assistance or accommodations with the application or interview process may contact University Human Resources/Faculty and Staff Disability Services, (319) 335-2660 or fsds@uiowa.edu. For jobs in UI Health care, please contact UI Health care Leave & Disability Administration at 319-356-7543.
