Research Specialist - Biochemistry & Molecular Biology
Biochemistry & Molecular Biology is seeking a full-time Research Specialist. This position requires collaborative work among across three research laboratories with the shared mission to elucidate mechanisms for how cells respond to force. The person in this position is responsible for the generation and interpretation of experimental data using techniques commonly used in the fields of cell biology, biochemistry, and molecular biology. Intermittent assistance with training students and maintenance of laboratory equipment is also part of the position duties. Key to this position is the demonstrated ability to work independently in the design, development, optimization and carrying out of experimental procedures, and conducting data analysis.
Research
- Function as a specialist/technical expert in a specific discipline.
- Investigate and perform critical analysis of current literature to develop novel approaches to research either independently or in conjunction with other investigators.
Experiments, Investigations, Evaluations
- Develop and implement research plan either independently or in conjunction with other investigators.
- Conduct complex research in a specialized discipline.
- Develop, troubleshoots and formulate protocols and hypotheses in a specialized field/discipline.
Collect, Analyze and Summarize Data; Prepare Reports: Contribute to Manuscripts, Publications
- Contribute at a high level to the lab/research project as evidenced by documented recognition in publications as an author or technical assistance.
- May independently write papers, manuscripts, grant applications, and publish.
- Develop new methodology and techniques related to the area of research.
- Develop the statistical analysis plan and oversee its implementation.
- Perform complex statistical analysis of data using advanced statistical methods and tools.
- Perform quantitative data analysis and summarize results.
- Present at local and national meetings.
Administrative and Project Management
- Oversee many of the administrative functions, including but not limited to writing and amending protocols, making decisions regarding the acquisition of equipment, software, and supplies, being responsible for safety programs, and managing staff.
- Communicate directly with any external stakeholders (funders, partners, etc.) as to progress, reporting requirements, and timetables.
Facilities and Equipment Management
- Determine needs of the lab and/or facilities.
- Gather and determine specifications for highly specialized equipment and procure lab equipment.
- Determine software needs for projects.
Supervision/Staffing
- Develop training procedures for basic and high-level lab techniques and protocols.
- Develop evaluation tools for measuring the outcomes of training, staff development, and staff performance.
- Hire staff and evaluate performance to assure compliance with UI policies and procedures.
Additional Responsibilities
- Generation and usage of mammalian cell lines and rodent models
- High resolution imaging of cells using light microscopy
- Protein isolation and western blot analysis
- Conduct metabolic assays, especially of mitochondrial function
- Rodent handling and colony maintenance
- Analyze and interpret data and determine the statistical significance results. Keep detailed laboratory notebooks recording experimental data and analyses and present these findings at periodic lab meetings. Recommend further experiments and/or changes in procedures
- Perform literature searches on topics studied, prepare research materials for reports, and assist in the preparation of papers for publication.
- Train other personnel in laboratory best practices
Pay Level: 5A
Professional and Scientific Pay Structures | University Human Resources - The University of Iowa
Required Qualifications:
- Bachelor's degree in biology, biochemistry, cell biology, molecular biology, chemistry, or molecular medicine or a combination of education and experience
- At least five years of experience working with laboratory mammalian cell culture and mice, such that one can perform high-level research in a natural or health science field or discipline is required
- Demonstrated record of scientific discovery by first authorship on manuscripts
- Experience in metabolic assays
- Experience in high resolution imaging using light microscopy
- Experience in protein isolation and western blot analysis
- Experience testing mitochondrial/metabolic function in cells and mice
- Experience managing colonies of research mice
- Experience working with cell culture model systems
- Excellent written and verbal communication skills are required
- Experience in written and oral data presentation
Desired Qualifications:
- Knowledge of the fundamental principles of metabolism, mitochondrial biology, biochemistry, and molecular biology
- Mastery of Mitochondria isolation, Oxygraph-2k respirometry, Seahorse Flux Analyzer
- Experience working with recombinant viral vectors
- Ability to provide technical instruction and mentorship to laboratory members of the team
- Ability to work independently
Application Process:
In order to be considered, applicants must upload a resume and cover letter (check the box for required attachment) that clearly address how they meet the listed required and desired qualifications of this position. Job openings are posted for a minimum of 14 calendar days.
Successful candidates must self-disclose any conviction history and will be subject to a criminal background check and education verification. This position is not eligible for University sponsorship for employment authorization. Please contact rosemary-stratton@uiowa.edu with any questions.
Equal opportunity/affirmative action employer
The University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, religion, national origin, age, sex, pregnancy (including childbirth and related conditions), disability, genetic information, status as a U.S. veteran, service in the U.S. military, sexual orientation, gender identity, or associational preferences.
Persons with disabilities who need assistance or accommodations with the application or interview process may contact University Human Resources/Faculty and Staff Disability Services, (319) 335-2660 or fsds@uiowa.edu. For jobs in UI Health care, please contact UI Health care Leave & Disability Administration at 319-356-7543.
